Nexium and imitrex interaction?

I take Nexium 40mg everyday for acid reflux and every so often i get bad migraines and take the imitrex shot or the 100mg pills.Also, I take Actonel every week for my bones. Please let me know if Quinine Sulfate will interact with these medications. Also, can u have alcoholic beverages on this medications. I NEVER drink but once in a blue moon at a family party I might have a half a pina colada. Will that effect the medication? Please get back to me as soon as possible about my other medications .

Thank you kindly,

Maryann