Tofranil (Oral)




Questions | Reviews

Weaning yourself off of Tofranil


I have been on Tofranil for about 8 years.   My doctor gave it to me for sleep but I am now retired and do not need to take it anymore.  I I am currently on 70 mgs. at bedtime.  Can you tell me how to wean  myself off of it th...
by Delores Bloom in Stow, Ohio, 05/04/2009

Tofranil and pregnancy


I am six months pregnant. I have been very depressed and decided with a doctor's help to take tofranil pm 75 for a month. What are the possible risks to the fetus? I am very concerned.
by Lana Simonetti, 08/04/2007

Tofranil (Oral) Drug and Prescription Information

Tofranil (Oral)

Tofranil (Oral) Medication Classification

IMIPRAMINE (By mouth)

Tofranil (Oral) Brandname

Tofranil, Tofranil-PM

Tofranil (Oral) is used for the Treatment

Imipramine (im-IP-ra-meen) Treats depression. May also be used to treat bedwetting in children.Belongs to a class of drugs called tricyclic antidepressants.

When To Not Use Tofranil (Oral)

You should not use this medicine if you have ever had an allergic reaction to it or to related medicine such as Elavil®, Aventyl®, Tegretol®, Ludiomil®, or Desyrel®. You should not take imipramine if you have had a recent heart attack or have taken an MAO inhibitor such as Nardil®, Marplan®, or Parnate® in the past 14 days.

How Should You Use Tofranil (Oral)

Capsule, Tablet

  • Your doctor will tell you how much medicine to take and how often.
  • Take with or without food.
  • Do not crush or chew the capsules. You may open the capsules and mix the medicine beads with soft food (pudding or applesauce). Swallow the mixture without chewing.
  • If you are taking this drug for depression, it may take 2 to 3 weeks before you start to feel better.
  • Do not stop taking this medicine suddenly. You may need to take smaller and smaller doses before completely stopping.
  • If a dose is missed:
  • Take the missed dose as soon as possible.
  • If it is almost time for your next dose, wait until then to take your medicine and skip the missed dose.
  • If you take one dose a day at bedtime, You should not use the missed dose the next morning. Wait until your next regular bedtime dose.
  • You should not use two doses at the same time.

Proper Tofranil (Oral) Storage

Store Tofranil (Oral) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep Tofranil (Oral) and all medications out of the reach of children.

What To Avoid While Using Tofranil (Oral)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not drink alcohol while you are taking imipramine.
  • Make sure your doctor knows if you are taking other drugs that can make you sleepy such as sleeping pills, sedatives, cold or allergy medicines, narcotic pain killers, muscle relaxants, or tranquilizers.
  • Make sure your doctor knows if you are taking medicine for high blood pressure.

Tofranil (Oral) Warnings

  • This medicine is harmful to use during pregnancy. It may cause birth defects.
  • Using this medicine while breastfeeding may cause drowsiness or other side effects in the nursing baby.
  • Tell your doctor if you have ever had glaucoma, trouble urinating, stomach problems, seizures, or heart, liver, kidney, or thyroid disease.
  • Do not give this medicine to a child unless directed to do so by the child's doctor.
  • This medicine may cause dizziness and vision changes. Avoid driving a car or operating machinery.
  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when outdoors. Avoid sunlamps and tanning beds.

Tofranil (Oral) Side Effects

Call your doctor right away if you notice any of these side effects:

  • Fainting
  • Fast, pounding or irregular heartbeat
  • Unexplained fever or sore throat
  • Skin rash
  • Trouble going to the bathroom (urinating)
  • If you notice these less serious side effects, talk with your doctor:
  • Dizziness or drowsiness
  • Dry mouth
  • Nausea, constipation
  • Weight gain
  • Changes in vision such as trouble focusing

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