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Triamcinolone
Triamcinolone (
Tablets: Aristocort, Kenacort)
Triamcinolone
(try-am-
SIN-oh-lohn)
Pregnancy Category: C
Dental Paste: Kenalog in Orabase
Oracort
Oralone
(Rx).
Tablets: Aristocort
Atolone
Kenacort
(Rx)
Triamcinolone acetonide
Triamcinolone acetonide (Kenalog, Aristocort)
Triamcinolone
(try-am-
SIN-oh-lohn)
Pregnancy Category: C
Dental Paste: Oracort
 .
Inhalation Aerosol: Azmacort
Nasacort
Nasacort AQ
(Rx).
Parenteral: Kenaject-40
Kenalog-10 and -40
Scheinpharm Triamcine-A
Tac-3 and -40
Triam-A
Triamonide 40
Tri-Kort
Trilog
(Rx).
Topical Aerosol: Kenalog
(Rx).
Topical Cream: Aristocort
Aristocort A
Delta-Tritex
Flutex
Kenac
Kenalog
Kenalog-H
Kenonel
Triacet
Triaderm
Trianide Mild
Trianide Regular
Triderm
Trymex
(Rx).
Topical Lotion: Kenalog
Kenonel
(Rx).
Topical Ointment: Aristocort
Aristocort A
Kenac
Kenalog
Kenonel
Triaderm
Trymex
Topical Spray: Nasacort AQ
(Rx)
Triamcinolone diacetate
Triamcinolone diacetate
Triamcinolone
(try-am-
SIN-oh-lohn)
Pregnancy Category: C
Parenteral: Amcort
Aristocort Forte
Aristocort Intralesional
Aristocort Parenteral
Articulose L.A.
Kenacort Diacetate
Triam-Forte
Triamolone 40
Trilone
Tristoject.
Syrup: Aristocort Syrup
(Rx)
Triamcinolone hexacetonide
Triamcinolone hexacetonide
Triamcinolone
(try-am-
SIN-oh-lohn)
Pregnancy Category: C
Aristospan Intra-Articular
Aristospan Intralesional
(Rx)
Classification:
Corticosteroid, synthetic
See Also:
See also
Corticosteroids
[.
]
Action/Kinetics:
More potent than prednisone. Intermediate-acting. Has no mineralocorticoid activity.
Onset: Several hours.
Duration: One or more weeks.
t
1/2: Over 200 min.
Additional Uses:
Pulmonary emphysema accompanied by bronchospasm or bronchial edema. Diffuse interstitial pulmonary fibrosis. With diuretics to treat refractory CHF or cirrhosis of the liver with ascites. Multiple sclerosis. Inflammation following dental procedures.
Triamcinolone acetonide: PO inhalation is used for maintenance treatment of asthma. Nasally for seasonal and perennial allergic rhinitis in adults and children 6 years and older.
Triamcinolone hexacetonide: Restricted to intra-articular or intralesional treatment of rheumatoid arthritis and osteoarthritis.
Special Concerns:
Use during pregnancy only if benefits clearly outweigh risks. Use with special caution with decreased renal function or renal disease. Dose must be highly individualized.
Additional Side Effects:
Intra-articular, intrasynovial, or intrabursal administration may cause transient flushing, dizziness, local depigmentation, and rarely, local irritation. Exacerbation of symptoms has also been reported. A marked increase in swelling and pain and further restricted joint movement may indicate septic arthritis. Intradermal injection may cause local vesicular ulceration and persistent scarring.
Syncope and anaphylactoid reactions have been reported with triamcinolone regardless of route of administration.
How Supplied:
Triamcinolone:
Tablet: 1 mg, 2 mg, 4 mg, 8 mg.
Triamcinolone acetonide:
Metered dose inhaler (nasal): 55 mcg/inh;
Metered dose inhaler (oral) 100 mcg/inh;
Cream: 0.025%, 0.1%, 0.5%;
Nasal Spray: Injection: 3 mg/mL, 10 mg/mL, 40 mg/mL;
Lotion: 0.025%, 0.1%;
Ointment: 0.025%, 0.05%, 0.1%, 0.5%;
Paste: 0.1%, 55 mcg/inh;
Topical Spray: 0.147 mg/g.
Triamcinolone diacetate:
Injection: 25 mg/mL, 40 mg/mL.
Triamcinolone hexacetonide:
Injection: 5 mg/mL, 20 mg/mL.
Dosage
Triamcinolone
?Tablets
Adrenocortical insufficiency (with mineralocorticoid therapy).
4-12 mg/day.
Acute leukemias (children).
1-2 mg/kg.
Acute leukemia or lymphoma (adults).
16-40 mg/day (up to 100 mg/day may be necessary for leukemia).
Edema.
16-20 mg (up to 48 mg may be required until diuresis occurs).
Tuberculosis meningitis.
32-48 mg/day.
Rheumatic disease, dermatologic disorders, bronchial asthma.
8-16 mg/day.
SLE.
20-32 mg/day.
Allergies.
8-12 mg/day.
Hematologic disorders.
16-60 mg/day.
Ophthalmologic diseases.
12-40 mg daily.
Respiratory diseases.
16-48 mg/day.
Triamcinolone acetonide
?IM Only (Not for IV Use)
2.5-60 mg/day, depending on the disease and its severity.
?Intra-articular, Intrabursal, Tendon Sheaths
2.5-5 mg for smaller joints and 5-15 mg for larger joints, although up to 40 mg has been used.
?Intradermal
1 mg/injection site (use 3 mg/mL or 10 mg/mL suspension only).
?Topical: 0.025%, 0.1%, 0.5% Ointment or Cream; 0.025%, 0.1% Lotion; Paste: 0.1%; Aerosol--to deliver 0.2 mg)
Apply sparingly to affected area b.i.d.-q.i.d. and rub in lightly.
?Metered Dose Inhaler (Azmacort)
Adults, usual: 2 inhalations (200 mcg) t.i.d.-q.i.d. or 4 inhalations (400 mcg) b.i.d., not to exceed 1,600 mcg/day. High initial doses (1,200-1,600 mcg/day) may be needed in some clients with severe asthma.
Pediatric, 6-12 years: 1-2 inhalations (100-200 mcg) t.i.d.-q.i.d. or 2-4 inhalations b.i.d., not to exceed 1,200 mcg/day. Use in children less than 6 years of age has not been determined.
?Intranasal Spray (Nasacort, Nasacort AQ)
Seasonal and perennial allergic rhinitis.
Adults and children over 6 years of age: 2 sprays (110 mcg) into each nostril once a day (i.e., for a total dose of 220 mcg/day). In adults, the dose may be increased to 440 mcg/day given either once daily or q.i.d. (1 spray/nostril). If using Nasacort AQ in children, start with 110 mcg/day given as 1 spray in each nostril/day; maximum dose is 220 mcg/day as 2 sprays/nostril once daily.
Triamcinolone diacetate
?IM Only
40 mg/week.
?Intra-articular, Intrasynovial
5-40 mg.
?Intralesional, Sublesional
5-48 mg (no more than 12.5 mg/injection site and 25 mg/lesion).
Triamcinolone hexacetonide
Not for IV use.
?Intra-articular
2-6 mg for small joints and 10-20 mg for large joints.
?Intralesional/Sublesional
Up to 0.5 mg/sq. in. of affected area. |
