Telmisartan
Telmisartan (Micardis)
Telmisartan
( tell-mih- SAR-tan)
Pregnancy Category: C (first trimester), D (second and third trimesters) Micardis (Rx)

Classification: Antihypertensive, angiotensin II receptor antagonist

See Also: See also Angiotensin II Receptor Antagonists and Antihypertensives.

Action/Kinetics: Over 99.5% bound to plasma protein. Control of BP in blacks is less than in whites. t 1/2, terminal: About 24 hr. Excreted mainly in the feces by way of the bile.

Uses: Treat hypertension

Special Concerns: Use with caution in impaired hepatic function or in biliary obstructive disorders.

Side Effects: GI: Diarrhea, dyspepsia, heartburn, N&V;, abdominal pain. CNS: Dizziness, headache, fatigue, anxiety, nervousness. Musculoskeletal: Pain, including back and neck pain; myalgia. Respiratory: URI, sinusitis, cough, pharyngitis, influenza. Miscellaneous: Chest pain, UTI, peripheral edema, hypertension.

Laboratory Test Alterations: Creatinine (in small number of clients). Hemoglobin.

Overdose Management: Symptoms: Hypotension, dizziness, tachycardia or bradycardia. Treatment: Supportive for hypotension.

Drug Interactions: Digoxin peak plasma and trough levels.

How Supplied: Tablets: 40 mg, 80 mg

Dosage
?Tablets Antihypertensive.
Adults, initial: 40 mg/day. Maintenance: 20-80 mg/day. If additional BP reduction is desired beyond that achieved with 80 mg/day, add a diuretic.