Spectinomycin hydrochloride




Questions | Reviews ****~

We don't currently have any questions about Spectinomycin hydrochloride.

Spectinomycin hydrochloride
Spectinomycin hydrochloride (Trobicin)
Spectinomycin hydrochloride
(speck-tin-oh- MY-sin)
Pregnancy Category: B Trobicin (Rx)

Classification: Antibiotic, miscellaneous

See Also: See also Anti-Infectives .

Action/Kinetics: Produced by Streptomyces spectabilis. It inhibits bacterial protein synthesis by binding to ribosomes (30S subunit), thereby interfering with transmission of genetic information crucial to life of microorganism. Mainly bacteriostatic. Only given IM. Peak plasma concentration: 100 mcg/mL (2-g dose) after 1 hr and 160 mcg/mL (4-g dose) after 2 hr. t 1/2: 1.2-2.8 hr. Not significantly bound to protein. Excreted in urine.

Uses: Acute gonorrheal proctitis and urethritis in males and acute gonorrheal cervicitis and proctitis in females due to susceptible strains of Neisseria gonorrhoeae. For pharyngeal infections, use only in those intolerant to cephalosporins or quinolones. It is ineffective against pharyngeal infections and against syphilis; is a poor drug to choose when mixed infections are present.

Contraindications: Sensitivity to drug.

Special Concerns: Safe use during pregnancy, in infants, and in children has not been established. Benzyl alcohol in the product may cause a fatal gasping syndrome in infants.

Side Effects: A single dose of spectinomycin has caused soreness at the site of injection, urticaria, dizziness, nausea, chills, fever, and insomnia. Multiple doses have caused a decrease in H&H; and C CR and an increase in alkaline phosphatase, BUN, and ALT. In single or multiple doses, decrease in urine output.

How Supplied: Powder for injection: 2 g

Dosage
?IM Only Gonorrheal urethritis in males, proctitis, and cervicitis.
2 g. In geographic areas where antibiotic resistance is known to be prevalent, give 4 g divided between two gluteal injection sites.
Alternative regimen for urethral, endocervical, or rectal gonococcal infections in clients who cannot take ceftriaxone.
Adults and children weighing more than 45 kg: Spectinomycin, 2 g, as a single dose followed by doxycycline. Children weighing less than 45 kg: 40 mg/kg given IM once.
Gonococcal infections in pregnancy where client is allergic to beta-lactams.
2 g followed by erythromycin.
Disseminated gonococcal infection where client is allergic to beta-lactams.
2 g q 12 hr.

Spectinomycin hydrochloride Ratings

Overall Rating:

4.5****~

 

(based on 1 review)

Effectiveness:

*****

Ease of Use:

****

Overall Satisfaction:

****

Reviewit

Reviews

Spectinomycin hydrochloride
4.5

Effectiveness: *****

Ease of Use: ****

Overall Satisfaction: ****

Avatar_thumbnail

New Air Jordans, New Air Jordans - 06/15/2012

We are professional and experienced fashion Air Jordan Shoes dealers and we've been doing this for many years. Here is the wonderland Air Jordan 2012 of all kinds of cheap and high quality Nike Wholesale products. All Jordans the items displayed here come from famous brands like Cheap Jordans, Nike Air Max, Nike Shox, Nike Free Shoes, Air Jordan Shoes, Nike Dunk SB, Nike Blazer, Nike Air Rifts, Nike Air Force Ones, Jordan Air Max Fusion and so on. A fast michael jordan shoes and boundless delivery, it is available here for all items sold which would arrive Air Jordan Retro in 5-7 work days. Moreover, we offer a good refund system in 30 days with no reasons. What we Air Jordan Shoes are doing is to give our customers the best at the lowest cost.

2 comments | Reply

Avatar_thumbnail

wfQaatYyniK, wfQaatYyniK - 11/04/2012

wpIaboZzfdQWtz <a href=http://monclerjacketso.moonfruit.com/>moncler men jackets</a> wfHnsaKcktLDqj <a href=http://monclerjacketso.moonfruit.com/>moncler women</a> wqBijbSbtsUYis <a href=http://monclerjacketso.moonfruit.com/>moncler jackets</a> waXpkvBclgVVyk <a href=http://monclermenjackets.moonfruit.com>moncler jackets</a> wsLxewIpfvBEiy <a href=http://monclermenjackets.moonfruit.com>moncler coats</a> wwPcxhFurwLVmi <a href=http://monclermenjackets.moonfruit.com>moncler jackets</a> wxSdhbHlzaISrr <a href=http://monclersjackets.moonfruit.com>moncler jackets</a> wiBhfsChprIYul <a href=http://monclersjackets.moonfruit.com>moncler jackets on sale</a> wqDlyqAnocQYac <a href=http://monclersjackets.moonfruit.com>moncler down jackets</a>

Avatar_thumbnail

wdHlsyDggsX, wdHlsyDggsX - 11/10/2012

wjXgenZwonPLwa <a href=http://moncleroutletsk.moonfruit.com/>moncler outlets</a> wxVuntGjquSSbd <a href=http://moncleroutletsk.moonfruit.com/>moncler outlet</a> wqDqweFoiaDAbd http://moncleroutletsk.moonfruit.com wwFistCzxvMQsf <a href=http://monclerjacketsb.moonfruit.com/>moncler jackets</a> wjTjbcFqvkKJis <a href=http://monclerjacketsb.moonfruit.com/>moncler coats</a> wxGkthFwbqLAon http://monclerjacketsb.moonfruit.com weGckoOehoNFnh <a href=http://tinyurl.com/ajnlmom>2012 nfl jerseys</a> wdVatkAevlVZin <a href=http://tinyurl.com/ajnlmom>nfl jerseys for sale</a> waEcrwEcozJCio <a href=http://tinyurl.com/ajnlmom>nfl jerseys china</a> whJivrJrcnZBgp <a href=http://monclerwomens.moonfruit.com>moncler womens jackets</a> wyYzcaGtmrQXma <a href=http://monclerwomens.moonfruit.com>moncler womens coats</a> wdEqdhHnhnHSeh http://monclerwomens.moonfruit.com