Mesoridazine besylate
Mesoridazine besylate (Serentil)
Mesoridazine besylate
(mez-oh-
RID-ah-zeen)
Serentil
(Rx)
Classification:
Antipsychotic, piperidine-type phenothiazine
See Also:
See also
Antipsychotic Agents, Phenothiazines
[.
]
Action/Kinetics:
Pronounced sedative and hypotensive effects, moderate anticholinergic effects, and a low incidence of extrapyramidal symptoms and antiemetic effects.
Uses:
Schizophrenia, acute and chronic alcoholism, behavior problems in clients with mental deficiency and chronic brain syndrome, psychoneurosis.
Special Concerns:
Use during pregnancy only if benefits clearly outweigh risks. Dosage has not been established in children less than 12 years of age. Geriatric, debilitated, and emaciated clients require a lower initial dose.
How Supplied:
Concentrate: 25 mg/mL;
Injection: 25 mg/mL;
Tablet: 10 mg, 25 mg, 50 mg, 100 mg
Dosage
?Oral Solution, Tablets
Psychotic disorders.
Adults and adolescents, initial: 50 mg t.i.d.;
optimum total dose: 100-400 mg/day.
Alcoholism.
Adults, initial: 25 mg b.i.d.;
optimum total dose: 50-200 mg/day.
Behavior problems in mental deficiency and chronic brain syndrome.
Adults, initial: 25 mg b.i.d.;
optimum total dose: 75-300 mg/day.
Psychoneurotic manifestations.
Adults, initial: 10 mg t.i.d.;
optimum total dose: 30-150 mg/day.
?IM
Psychotic disorders.
Adults and adolescents, initial: 25 mg (base);
then, repeat the dose in 30-60 min as needed.
Optimum total dose: 25-200 mg/day. |