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Ferrous sulfate Dosage, Interactions, Side Effects, How to Use


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ferrous sulfate side effect I took this medicine  and in 3 1/2 weeks I suddenly was gasping for air could not breath and when I did take a breath my chest pained me incredably and my throat was closed to the point that I could not swallow. My Dr. said he knew of no one that... by e. bella in St. Petersburg, Florida, 10/06/2009

Ferrous sulfate Dosage, Interactions, Side Effects, How to Use Questions

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Iron Deffficience When I take the Ferrous Sulfate, I get a little light headed and quizzy stomach. Is this a side effect or should I eat before I take the medicine? by Brenda in Barnwell, South Carolina, 05/17/2010

expiration date of this medication I have a older prescription of this and I am wondering how long these are good. I am to start taking them again. Do you know how long the shelf life is on them?I got them in 11/08 and there is no expiration date on them. Thank You by Jody in usa, 05/05/2010

How long will it be before I should get Iron studies again I have take ferrous sulfate 325mg bid for one month. My hgb was 9 when I started and was up to 9.2 after 2 weeks. Original Iron studies were as follows Iron 12 Total Iron binding 447 Iron Saturation 3 When should I have my hgb rechecked and when... by Denise Brock in Sioux Falls, SD, 04/25/2010

Recommended Dosage I have received the round green 325mg tablets, and is 3x a day, 975mg too much to take in daily? And with this dosage, is there a risk of side effects? by Pamela Friloux in California, 02/28/2010

Should this be prescribed to those with Thallesemia I have been diagnosed with thallesemia, a blood disorder which is affected by iron in the diet.  It originates from eastern meditteranean countries and is hereditary.  I was recently hospitalized and they prescribed ferrous sulfate which I b... by Randall Q. Coleman in Bowie, TX -- USA, 02/24/2010

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Ferrous sulfate
Ferrous sulfate (Feosol)
Ferrous sulfate
( FAIR-us SUL-fayt) Apo-Ferrous Sulfate Feosol Fer-gen-sol Fer-in-Sol Fer-Iron Ferrodan Fero-Grad PMS Ferrous Sulfate (OTC)
Ferrous sulfate, dried
Ferrous sulfate, dried
Ferrous sulfate
( FAIR-us SUL-fayt) Fe 50 Feosol Feratab Slow FE (OTC)

Classification: Antianemic, iron

Action/Kinetics: The normal daily iron intake for males is 12-20 mg and for females is 8-15 mg, although only about 10% (1-2 mg) of this iron is absorbed. Iron is absorbed from the duodenum and upper jejunum by an active mechanism through the mucosal cells where it combines with the protein transferrin. Iron is stored in the body as hemosiderin or aggregated ferritin which is found in reticuloendothelial cells of the liver, spleen, and bone marrow. About two-thirds of total body iron is in the circulating RBCs in hemoglobin. Absorption is enhanced when stored iron is depleted or when erythropoesis occurs at an increased rate. Food decreases iron absorption by up to two-thirds. The daily loss of iron through urine, sweat, and sloughing of intestinal mucosal cells is 0.5-1 mg in healthy men; in menstruating women, 1-2 mg is the normal daily loss. Least expensive, most effective iron salt for PO therapy. Ferrous sulfate products contain 20% elemental iron, whereas ferrous sulfate dried products contain 30% elemental iron. The exsiccated form is more stable in air.

Uses: Prophylaxis and treatment of iron deficiency and iron-deficiency anemias. Dietary supplement for iron. Optimum therapeutic responses are usually noted within 2-4 weeks. Investigational: Clients receiving epoetin therapy (failure to give iron supplements either IV or PO can impair the hematologic response to epoetin).

Contraindications: Hemosiderosis, hemochromatosis, peptic ulcer, regional enteritis, and ulcerative colitis. Hemolytic anemia, pyridoxine-responsive anemia, and cirrhosis of the liver. Use in those with normal iron balance.

Special Concerns: Allergic reactions may result due to certain products containing tartrazine and some products containing sulfites.

Side Effects: GI: Constipation, gastric irritation, nausea, abdominal cramps, anorexia, vomiting, diarrhea, dark-colored stools. These effects may be minimized by administering preparations as a coated tablet. Soluble iron preparations may stain the teeth.

Laboratory Test Alterations: Iron may affect electrolyte balance determinations.

Overdose Management: Symptoms: Symptoms occur in four stages--(1) Lethargy, N&V;, abdominal pain, weak and rapid pulse, tarry stools, dehydration, acidosis, hypotension, and coma within 1-6 hr. (2) If client survives, symptoms subside for about 24 hr. (3) Within 24-48 hr symptoms return with diffuse vascular congestion, shock, pulmonary edema, acidosis, seizures, anuria, hyperthermia, and death. (4) If client survives, pyloric or antral stenosis, hepatic cirrhosis, and CNS damage are seen within 2-6 weeks. Toxic reactions are more likely to occur after parenteral administration. Treatment (Iron Toxicity): General supportive measures. Maintain a patent airway, respiration, and circulation. Induce vomiting with syrup of ipecac followed by gastric lavage using tepid water or 1%-5% sodium bicarbonate (to convert from ferrous sulfate to ferrous carbonate, which is poorly absorbed and less irritating). Saline cathartics can also be used. Deferoxamine is indicated for clients with serum iron levels greater than 300 mg/dL. Deferoxamine is usually given IM, but in severe cases of poisoning it may be given IV. Hydration should be maintained. It may be necessary to treat for shock, acidosis, renal failure, and seizures.

Drug Interactions: Antacids, oral / Iron absorption from GI tract Ascorbic acid / Ascorbic acid, 200 mg or more, iron absorption Chloramphenicol / Serum iron levels Cholestyramine / Iron absoprtion from GI tract Cimetidine / Iron absorption from GI tract Fluoroquinolones / Fluoroquinolone absorption from GI tract R/T formation of a ferric ion-quinolone complex Levodopa / Levodopa absorption R/T formation of chelates with iron salts Levothyroxine / Levothyroxine efficacy Methyldopa / Methyldopa absorption from GI tract Pancreatic extracts / Iron absorption from GI tract Penicillamine / Penicillamine absorption from GI tract due to chelation St. John's wort / May absorption of iron Tetracyclines / Absorption of both tetracyclines and iron from GI tract Vitamin E / Response to iron therapy

How Supplied: Ferrous sulfate: Capsule: 250 mg, 324 mg; Capsule, Extended Release: 250 mg; Elixir: 220 mg/5 mL; Enteric Coated Tablet: 325 mg; Liquid: 25 mg/mL, 75 mg/0.6 mL, 300 mg/5 mL; Solution: 300 mg/5 mL; Syrup: 90 mg/5 mL; Tablet: 195 mg, 300 mg, 324 mg, 325 mg; Tablet, Extended Release: 250 mg, 525 mg Ferrous sulfate, dried: Capsule, Extended Release: 150 mg, 159 mg; Enteric Coated Tablet: 200 mg; Tablet: 200 mg; Tablet, Extended Release: 152 mg, 159 mg, 160 mg

Dosage
Ferrous Sulfate ?Extended-Release Capsules
Adults: 150-250 mg 1-2 times/day. This dosage form is not recommended for children.
?Elixir, Oral Solution, Tablets, Enteric-coated Tablets Prophylaxis.
Adults: 300 mg/day. Pediatric: 5 mg/kg/day.
Anemia.
Adults: 300 mg b.i.d. increased to 300 mg q.i.d. as needed and tolerated. Pediatric: 10 mg/kg t.i.d. The enteric-coated tablets are not recommended for use in children.
?Extended-Release Tablets
Adults: 525 mg 1-2 times/day. This dosage form is not recommended for use in children.
Ferrous Sulfate, Dried ?Capsules Prophylaxis.
Adults: 300 mg/day. Pediatric: 5 mg/kg/day.
Anemia.
Adults: 300 mg b.i.d. up to 300 mg q.i.d. as needed and tolerated. Pediatric: 10 mg/kg t.i.d.
?Tablets Prophylaxis.
Adults: 200 mg/day. Pediatric: 5 mg/kg/day.
Anemia.
Adults: 200 mg t.i.d. up to 200 mg q.i.d. as needed and tolerated. Pediatric: 10 mg/kg t.i.d.
?Extended-Release Tablets
Adults: 160 mg 1-2 times/day. This dosage form is not recommended for use in children.