Dicloxacillin sodium




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Dicloxacillin sodium
Dicloxacillin sodium (Dynapen)
Dicloxacillin sodium
(dye-klox-ah- SILL-in)
Pregnancy Category: B Dycill Dynapen Pathocil (Rx)

Classification: Antibiotic, penicillin

See Also: See also Anti-Infectives and Penicillins .

Action/Kinetics: Penicillinase-resistant and acid-stable. Peak serum levels: IM, PO, 4-20 mcg/mL after 1 hr. t 1/2: 40 min. 98% bound to plasma proteins. Chiefly excreted in urine.

Uses: Infections due to penicillinase-producing staphylococci. To initiate therapy in any suspected staphylococcal infection. Infections due to Streptococcus pneumoniae.

Contraindications: Treatment of meningitis. Use in newborns.

How Supplied: Capsule: 250 mg, 500 mg; Powder for reconstitution: 62.5 mg/5 mL

Dosage
?Capsules, Oral Suspension Skin and soft tissue infections, mild to moderate URTIs.
Adults and children over 40 kg: 125 mg q 6 hr; pediatric, less than 40 kg: 12.5 mg/kg/day in four equal doses given q 6 hr.
More severe lower respiratory tract infections or disseminated infections.
Adults and children over 40 kg: 250 mg q 6 hr, up to a maximum of 4 g/day; pediatric, less than 40 kg: 25 mg/kg/day in four equal doses given q 6 hr.

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