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Cefpodoxime proxetil
Cefpodoxime proxetil (Vantin)
Cefpodoxime proxetil
(sef-poh-
DOX-eem)
Pregnancy Category: B
Vantin
(Rx)
Classification:
Cephalosporin, third-generation
See Also:
See also
Anti-Infectives and
Cephalosporins
[.
]
Action/Kinetics:
t
1/2,
after PO: 2-3 hr. From 29% to 33% is excreted unchanged in the urine.
Uses:
(1) Acute, community-acquired pneumonia due to
Streptococcus pneumoniae or
Hemophilus influenzae (non-ß-lactamase-producing strains only). (2) Acute bacterial exacerbation of chronic bronchitis caused by
S. pneumoniae non-beta-lactamase-producing
H. influenzae or
M. catarrhalis. (3) Acute otitis media caused by
S. pneumoniae, H. influenzae (including beta-lactamase-producing strains), and
Moraxella catarrhalis. (4) Pharyngitis or tonsillitis due to
Streptococcus pyogenes. (5) Acute, uncomplicated urethral and cervical gonorrhea caused by
Neisseria gonorrhoeae (including penicillinase-producing strains). (6) Acute, uncomplicated anorectal infections in women due to
N. gonorrhoeae (including penicillinase-producing strains). (7) Uncomplicated skin and skin structure infections due to
Staphylococcus aureus (including penicillinase-producing strains) or
S. pyogenes. (8) Uncomplicated UTIs (cystitis) due to
Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis or
Staphyloccus saprophyticus. (9) Mild-to-moderate acute maxillary sinusitis.
How Supplied:
Granule for Reconstitution: 50 mg/5 mL, 100 mg/5 mL;
Tablet: 100 mg, 200 mg
Dosage
?Tablets, Suspension
Acute community-acquired pneumonia.
Adults and children over 13 years: 200 mg q 12 hr for 14 days.
Acute bacterial exacerbations of chronic bronchitis.
Adults and children over 13 years: 200 mg q 12 hr for 10 days. Use the tablets.
Uncomplicated gonorrhea (men and women) and rectal gonococcal infections (women).
Adults and children over 13 years: Single dose of 200 mg.
Skin and skin structure infections.
Adults and children over 13 years: 400 mg q 12 hr for 7-14 days.
Pharyngitis, tonsillitis.
Adults and children over 13 years: 100 mg q 12 hr for 5-10 days.
Children, 5 months-12 years: 5 mg/kg (maximum of 100 mg/dose) q 12 hr (maximum daily dose: 200 mg) for 5-10 days.
Uncomplicated UTIs.
Adults and children over 13 years: 100 mg q 12 hr for 7 days.
Acute otitis media.
Children, 2 months-12 years: 5 mg/kg q 12 hr for 5 days. |
