bkdaniels
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Jun 24, 2005, 10:42 AM
Post #4 of 4
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Hey mark m, how are you doing? Kales and Kales found only FLURAZEPAM (DalmaneŽ) to retain its power of reducing sleep latency and awake time after sleep onset. Other fairly quick-acting , rapidly destroyed hypnotic such as secobarbital (Seconal), 30 to 60 mg, chloral hydrate (Noctec), 500 to 1,00 mg, glutethimide (Doriden), 500 mg, or methaqualone (Sopor), 150 to 300 mg, given 15 to 30 minutes before going to bed is useful in inducing and maintaining sleep, but after a week of two, however, their effects wanes. Of all the conditions that make for human efficiency and sense of well-being, sleep is one of the most important. Deprived of sleep, experimental animals will die within a few days, no matter how well they are fed, watered, and housed; under similar circumstances human beings suffer a variety of unpleasant symptoms that must be separated from the disease of insominia. Human beings deprived of sleep (NREM and REM) for periods of 60 to 200 h experience fatigue and irritability and find it difficult to concentrate, to percieve accurately, and to maintain their orientation. Illusions and hallucinations intrude into consciousness, primarily in the visual and tactile sensory fields, becoming more intense as the period of sleeplessness is prolonged. Performance of motor tasks deteriorates; incentive to work weakens, and sustained action is interrupted by lapses of attention. Recovery after prolonged sleep deprivation shows that the amount of sleep required is never equal to the amount lost. REFERENCES Nancy J. Rennert, M.D.,: Myxedema Endocrinology, Yale University School of Medicine, New Haven, CT., 4/2004 American Academy of Family Physicians: Mass Psychogenic Illness Kales A, Kales JD: Recent findings in the diagnosis and treatment of disturbed sleep. New Engl J Med 290:487, 1974 Best wishes, The Prison Hospital Prisoner: Look here, doctor! You've already removed my spleen, tonsils, adenoids, and one of my kidneys. I only came to see if you could get me out of this place! Doctor: I am, bit by bit. -- Aha! Jokes
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