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Trimipramine maleate
Trimipramine maleate (Surmontil)
Trimipramine maleate
(try-MIP-rah-meen)
Pregnancy Category: C
Apo-Trimip
Novo-Tripramine
Nu-Trimipramine
Rhotrimine
Surmontil
(Rx)
Classification:
Antidepressant, tricyclic
See Also:
See also Antidepressants, Tricyclic[.
]Action/Kinetics:
Causes moderate anticholinergic and orthostatic hypotensive effects and significant sedative effects. Effective plasma levels: 180 ng/mL. Time to reach steady state: 2-6 days. t1/2: 7-30 hr.
Uses:
Treatment of symptoms of depression. PUD. Seems more effective in endogenous depression than in other types of depression.
Contraindications:
Use in children less than 12 years of age.
How Supplied:
Capsule: 25 mg, 50 mg, 100 mg
Dosage
•Capsules
Antidepressant.
Adults, outpatients, initial: 75 mg/day in divided doses up to 150 mg/day, but not to exceed 200 mg/day; maintenance: 50-150 mg/day. Total dose can be given at bedtime. Adults, hospitalized, initial: 100 mg/day in divided doses up to 200 mg/day. If no improvement in 2-3 weeks, increase to 250-300 mg/day. Adolescent/geriatric clients, initial: 50 mg/day up to 100 mg/day. Not recommended for children. |
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