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Telmisartan
Telmisartan (Micardis)
Telmisartan
(tell-mih-SAR-tan)
Pregnancy Category: C (first trimester), D (second and third trimesters)
Micardis (Rx)
Classification:
Antihypertensive, angiotensin II receptor antagonist
See Also:
See also Angiotensin II Receptor Antagonists and Antihypertensives.
Action/Kinetics:
Over 99.5% bound to plasma protein. Control of BP in blacks is less than in whites. t1/2, terminal: About 24 hr. Excreted mainly in the feces by way of the bile.
Uses:
Treat hypertension
Special Concerns:
Use with caution in impaired hepatic function or in biliary obstructive disorders.
Side Effects:
GI: Diarrhea, dyspepsia, heartburn, N&V;, abdominal pain. CNS: Dizziness, headache, fatigue, anxiety, nervousness. Musculoskeletal: Pain, including back and neck pain; myalgia. Respiratory: URI, sinusitis, cough, pharyngitis, influenza. Miscellaneous: Chest pain, UTI, peripheral edema, hypertension.
Laboratory Test Alterations:
Creatinine (in small number of clients). Hemoglobin.
Overdose Management:
Symptoms: Hypotension, dizziness, tachycardia or bradycardia. Treatment: Supportive for hypotension.
Drug Interactions:
Digoxin peak plasma and trough levels.
How Supplied:
Tablets: 40 mg, 80 mg
Dosage
•Tablets
Antihypertensive.
Adults, initial: 40 mg/day. Maintenance: 20-80 mg/day. If additional BP reduction is desired beyond that achieved with 80 mg/day, add a diuretic.
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