[.
]Action/Kinetics:
By inhibiting prostaglandin synthesis, suprofen reverses prostaglandin-induced vasodilation, leukocytosis, increased vascular permeability, and increased intraocular pressure. Also inhibits miosis, which occurs during cataract surgery.
Uses:
Inhibition of intraoperative miosis.
Contraindications:
Dendritic keratitis.
Special Concerns:
Use with caution during lactation, in clients sensitive to aspirin and other NSAIDs, and in surgical clients with a history of bleeding tendencies or who are on drugs that prolong bleeding time. Safety and efficacy have not been established in children.
Side Effects:
Ophthalmic: Ocular irritation, transient burning, and stinging on installation. Redness, itching, discomfort, pain, iritis, allergy, chemosis, photophobia, punctate epithelial staining.
Drug Interactions:
Acetylcholine and carbachol may be ineffective if used in combination with suprofen.
How Supplied:
Solution: 1%
Dosage
•Ophthalmic Solution
Day before surgery.
2 gtt into the conjunctival sac q 4 hr during waking hours.
Day of surgery.
2 gtt into the conjunctival sac 3, 2, and 1 hr prior to surgery.
