[.
]Action/Kinetics:
Has both beta-1- and beta-2-receptor blocking activity. It has no membrane-stabilizing activity but does possess minimal intrinsic sympathomimetic activity. High lipid solubility. t1/2: 5 hr. 80%-98% protein bound. Metabolized in the liver and excreted through the urine.
Uses:
Mild to moderate arterial hypertension.
Contraindications:
Bronchial asthma or bronchospasms, including severe COPD.
Special Concerns:
Dosage has not been established in children. Geriatric clients may manifest increased or decreased sensitivity to the usual adult dose.
How Supplied:
Tablet: 20 mg
Dosage
•Tablets
Hypertension.
Initial: 20 mg/day either alone or with other antihypertensive agents. Maintenance: Same as initial dose. Doses greater than 40 mg/day do not result in a greater antihypertensive effect.