Lamivudine/Zidovudine
Lamivudine/Zidovudine (Combivir)
Lamivudine/Zidovudine
((lah-MIH-vyou-deen, zye-DOH-vyou-deen))
Pregnancy Category: C Combivir (Rx)

Classification: Antiviral drug combination

See Also: See also Lamivudine, Zidovudine, and Antiviral Drugs.

Content: Each Combivir tablet contains: Antiviral: Lamivudine, 150 mg and Antiviral: Zidovudine, 300 mg.

Action/Kinetics: Both drugs are reverse transcriptase inhibitors with activity against HIV. Combination results in synergistic antiretroviral effect. Each drug is rapidly absorbed.

Uses: Treatment of HIV infection.

Contraindications: Use in clients requiring dosage reduction, children less than 12 years of age, C_CR less than 50 mL/min, body weight less than 50 kg, and in those experiencing dose-limiting side effects.

Side Effects: See individual drugs.

How Supplied: See Content

Dosage
•Tablets HIV infection.
Adults and children over 12 years of age: One combination tablet--150 mg lamivudine/300 mg zidovudine--b.i.d.