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Hydrocortisone
(Cortisol)
Hydrocortisone (Hydrocortone, Cort-Dome)
Cortisol (Hydrocortone, Cort-Dome)
Hydrocortisone
(hy-droh-KOR-tih-zohn)
Pregnancy Category: C (topical and dental products) Parenteral: Sterile Hydrocortisone Suspension. Rectal: Dermolate Anal-Itch Cortenema Proctocort ProctoCream.HC 2.5% Rectocort. Retention Enema: Cortenema Hycort Rectocort. Roll-on Applicator: Cortaid FastStick Maximum Strength Cortaid Faststick Tablets: Cortef Hydrocortone. Topical Cream: Ala-Cort Allercort Alphaderm Bactine Cortate Cort-Dome Cortifair Dermacort DermiCort Dermolate Anti-Itch Dermtex HC Emo-Cort H₂Cort Hi-Cor 1.0 and 2.5 Hydro-Tex Hytone Nutracort Penecort Prevex HC Synacort. Topical Gel: Extra Strength CortaGel Topical Liquid: Scalpicin T/Scalp Topical Lotion: Acticort 100 Ala-Cort Ala-Scalp Allercort Aquacort Cetacort Cortate Cort-Dome Delacort Dermacort Dermolate Scalp-Itch Emo-Cort Gly-Cort Hytone LactiCare-HC Lemoderm Lexocort Forte My Cort Nutracort Pentacort Rederm Sarna HC S-T Cort. Topical Ointment: Allercort Cortoderm Cortril Hytone Lemoderm Penecort. Topical Solution: Penecort Emo-Cort Scalp Solution Texacort Scalp Solution. Topical Spray: Cortaid Dermolate Anti-Itch Maximum Strength Coraid Procort (OTC) (Rx)
Hydrocortisone acetate
Hydrocortisone acetate (Orabase-HCA)
Hydrocortisone
(hy-droh-KOR-tih-zohn)
Pregnancy Category: C (topical and dental products) Dental Paste: Orabase-HCA. Intrarectal Foam: Cortifoam. Ophthalmic/Otic: Cortamed. Parenteral: Hydrocortone Acetate. Rectal: Cort-Dome High Potency Cortenema Corticaine Cortifoam. Suppository: Cortiment Rectocort Topical Cream: CaldeCORT Light Carmol-HC Cortaid Cortef Feminine Itch Corticaine Corticreme FoilleCort Gynecort Gynecort Female Cream Hyderm Lanacort Lanacort 10 Lanacort 5 Maximum Strength Cortaid Pharma-Cort Rhulicort. Topical Lotion: Cortaid Rhulicort. Topical Ointment: Anusol HC-1 Cortef Acetate Dermaflex HC 1% Lanacort Lanacort 5 Nov-Hydrocort. Maximum Strength Cortaid (OTC) (Rx)
Hydrocortisone butyrate
Hydrocortisone butyrate (Locoid)
Hydrocortisone
(hy-droh-KOR-tih-zohn)
Pregnancy Category: C (topical products) Topical Cream, Ointment, Solution: Locoid (Rx)
Hydrocortisone cypionate
Hydrocortisone cypionate (Cortef)
Hydrocortisone
(hy-droh-KOR-tih-zohn)
Pregnancy Category: C Oral Suspension: Cortef (Rx)
Hydrocortisone probutate
Hydrocortisone probutate (Pandel)
Hyrocortisone
(hy-droh-KOR-tih-zohn)
Pregnancy Category: C Topical Cream: Pandel (Rx)
Hydrocortisone sodium phosphate
Hydrocortisone sodium phosphate (Hydrocortone Phosphate)
Hydrocortisone
(hy-droh-KOR-tih-zohn)
Pregnancy Category: C Parenteral: Hydrocortone Phosphate (Rx)
Hydrocortisone sodium succinate
Hydrocortisone sodium succinate (Solu-Cortef)
Hydrocortisone
(hy-droh-KOR-tih-zohn)
Pregnancy Category: C Parenteral: A-hydroCort Solu-Cortef (Rx)
Hydrocortisone valerate
Hydrocortisone valerate (Westcort)
Hydrocortisone
(hy-droh-KOR-tih-zohn)
Pregnancy Category: C (topical products) Topical Cream/Ointment: Westcort (Rx)

Classification: Corticosteroid, naturally occurring; glucocorticoid-type

See Also: See also Corticosteroids.

Action/Kinetics: Short-acting. t1/2: 80-118 min. Topical products are available without a prescription in strengths of 0.5% and 1%.

How Supplied: Hydrocortisone Cortisol: Balm: 1%; Cream: 0.5%, 1%, 2.5%; Enema: 100 mg/60 mL; Gel/jelly: 1%; Liquid: 1%; Lotion: 0.25%, O.5%, 1%, 2%, 2.5%; Ointment: 0.5%, 1%, 2.5%; Pad: 0.5%, 1%; Solution: 1%, 2.5%; Spray: 1%; Tablet: 5 mg, 10 mg, 20 mg. Hydrocortisone acetate: Cream: 0.5%, 1%; Foam: 10%; Injection: 50 mg/mL; Ointment: 0.5%, 1%; Spray: 0.5%; Suppository: 25 mg, 30 mg. Hydrocortisone butyrate: Cream: 0.1%; Ointment: 0.1%; Solution: 0.1%. Hydrocortisone cypionate: Suspension: 10 mg/5 mL. Hydrocortisone probutate: Cream: 0.1%. Hydrocortisone sodium phosphate: Injection: 50 mg/mL. Hydrocortisone sodium succinate: Powder for injection: 100 mg, 250 mg, 500 mg, 1 g. Hydrocortisone valerate: Cream: 0.2%; Ointment: 0.2%.

Dosage
Hydrocortisone •Tablets
20-240 mg/day, depending on disease.
•IM Only
One-third to one-half the PO dose q 12 hr.
•Rectal
100 mg in retention enema nightly for 21 days (up to 2 months of therapy may be needed; discontinue gradually if therapy exceeds 3 weeks).
•Topical Ointment, Cream, Gel, Lotion, Solution, Spray
Apply sparingly to affected area and rub in lightly t.i.d.-q.i.d.
Hydrocortisone acetate •Intralesional, Intra-articular, Soft Tissue
5-50 mg, depending on condition.
•Intrarectal Foam
1 applicatorful (90 mg) 1-2 times/day for 2-3 weeks; then every second day.
•Topical
See Hydrocortisone.
Hydrocortisone butyrate •Topical Cream, Ointment, Solution
Apply a thin film to the affected area b.i.d.-t.i.d.
Hydrocortisone probutate •Topical Cream
Apply a thin film to the affected area 1-2 times/day.
Hydrocortisone cypionate •Suspension
20-240 mg/day, depending on the severity of the disease.
Hydrocortisone sodium phosphate •IV, IM, SC General uses.
Initial: 15-240 mg/day depending on use and on severity of the disease. Usually, one-half to one-third of the PO dose is given q 12 hr.
Adrenal insufficiency, acute.
Adults, initial: 100 mg IV; then, 100 mg q 8 hr in an IV fluid; older children, initial: 1-2 mg/kg by IV bolus; then, 150-250 mg/kg/day IV in divided doses; infants, initial: 1-2 mg/kg by IV bolus; then, 25-150 mg/kg/day in divided doses.
Hydrocortisone sodium succinate •IM, IV
Initial: 100-500 mg; then, may be repeated at 2-, 4-, and 6-hr intervals depending on response and severity of condition.
Hydrocortisone valerate •Topical Cream
See Hydrocortisone.