[.
]Action/Kinetics:
Acts by lowering the surface tension of the feces and promoting penetration by water and fat, thus increasing the softness of the fecal mass. Not absorbed systemically and does not seem to interfere with the absorption of nutrients. A microenema formulation is available for clients aged 3 and older. Onset: 24-72 hr.; onset, microenema formulation: 15 min.
Uses:
To lessen strain of defecation in persons with hernia or CV diseases or other diseases in which straining at stool should be avoided. Megacolon or bedridden clients. Constipation associated with dry, hard stools. The microemulsion formulation is indicated for relief of occasional constipation in children over the age of 3 years.
Contraindications:
Nausea, vomiting, abdominal pain, and intestinal obstruction.
Drug Interactions:
Docusate may 
absorption of mineral oil from the GI tract.
How Supplied:
Docusate calcium: Capsule: 240 mg. Docusate potassium: Capsule: 100 mg, 240 mg Docusate sodium: Capsule: 50 mg, 100 mg, 240 mg, 250 mg; Oral Liquid: 200 mg/5 mL, 150 mg/15 mL; Powder for Reconstitution: 283 mg; Solution: 100 mg/15 mL; Syrup: 50 mg/15 mL, 60 mg/15 mL; Tablet: 100 mg
Dosage
Docusate Calcium
•Capsules
Adults: 240 mg/day until bowel movements are normal; pediatric, over 6 years: 50-150 mg/day.
Docusate Potassium
•Capsules
Adults: 100-300 mg/day; pediatric, over 6 years: 100 mg at bedtime.
Docusate Sodium
•Capsules, Oral Liquid, Syrup, Tablets
Adults and children over 12 years: 50-500 mg; pediatric, under 3 years: 10-40 mg; 3-6 years: 20-60 mg; 6-12 years: 40-120 mg.
•Rectal Solution
Flushing or retention enema.
Adults: 50-100 mg.
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