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Isoetharine hydrochloride
Isoetharine hydrochloride
Isoetharine hydrochloride
(eye-so-ETH-ah-reen)
Pregnancy Category: C
(Rx)
Classification:
Adrenergic agent, bronchodilator
See Also:
See also Sympathomimetic Drugs.
Action/Kinetics:
Has a greater stimulating activity on beta-2 receptors of the bronchi than on beta-1 receptors of the heart. Causes relief of bronchospasms. Inhalation: Onset, within 5 min; peak effect: 15-60 min; duration: 2-3 hr. Partially metabolized; excreted in urine.
Uses:
Bronchial asthma, bronchospasms due to chronic bronchitis or emphysema, bronchiectasis, pulmonary obstructive disease.
Special Concerns:
Safety and efficacy have not been established in children less than 12 years of age.
How Supplied:
Isoetharine hydrochloride: Solution: 1%
Dosage
•Inhalation Solution, 1%
Hand nebulizer.
Adults: 3-7 inhalations of the undiluted solution.
Oxygen aerosolization.
Adults, usual: 0.5 mL (range: 1-2 mL of 1:3 dilution). Give with oxygen flow adjusted to 4-6 L/min over 15-20 min.
IPPB.
Adults, usual: 0.5 mL (range: 1-4 mL of 1:3 dilution). Usual inspiratory flow rate is 15 L/min at a cycling pressure of 15 cm H2O. May be necessary (depending on client and tyupe of IPPB apparatus) to adjust flow rate to 6-30 L/min and cycling pressure to 10-15 cm H2O (further dilution may also be required). |
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