Dextromethorphan hydrobromide
Dextromethorphan hydrobromide
Dextromethorphan hydrobromide
(dex-troh-meth- OR-fan) Balminil DM Children Balminil DM Syrup Benylin DM Benylin DM for Children Children's Hold Delsym Drixoral Cough Liquid Caps Hold DM Koffex DM Children Koffex DM Syrup Novahistex DM Novahistine DM Pertussin CS Pertussin ES Robitussin Cough Calmers Robitussin Pediatric St. Joseph Cough Suppressant Scot-Tussin DM Cough Chasers Sucrets Cough Control Suppress Triaminic DM Triaminic DM Long Lasting For Children Trocal Vick's Formula 44 Vick's Formula 44 Pediatric Formula (OTC)

Classification: Nonnarcotic antitussive

Action/Kinetics: Selectively depresses the cough center in the medulla. Dextromethorphan 15-30 mg is equal to 8-15 mg codeine as an antitussive. Does not produce physical dependence or respiratory depression. Well absorbed from GI tract. Onset: 15-30 min. Duration: 3-6 hr. The sustained liquid contains dextromethorphan plistirex equivalent to 30 mg dextromethorphan hydrobromide per 5 mL.

Uses: Symptomatic relief of nonproductive cough due to colds or inhaled irritants.

Contraindications: Persistent or chronic cough or when cough is accompanied by excessive secretions. Use during first trimester of pregnancy unless directed otherwise by physician. Use in children less than 2 years of age.

Special Concerns: Use with caution in clients with nausea, vomiting, high fever, rash, or persistent headache.

Side Effects: CNS: Dizziness, drowsiness. GI: N&V;, stomach pain.

Overdose Management: Symptoms: Adults: Dysphoria, slurred speech, ataxia, altered sensory perception. Children: Ataxia, convulsions, respiratory depression. Treatment: Treat symptoms and provide support.

Drug Interactions: Use with MAO inhibitors may cause nausea, hypotension, hyperpyrexia, myoclonic leg jerks, and coma.

How Supplied: Concentrate: 40 mg/5 mL; Liquid: 3.5 mg/5 mL, 5 mg/5 mL, 7.5 mg/5 mL, 15 mg/5 mL; Lozenge/troche: 2.5 mg, 5 mg, 15 mg; Suspension, Extended Release: 30 mg/5 mL; Syrup: 3.5 mg/5 mL, 5 mg/5 mL, 7.5 mg/5 mL, 10 mg/5 mL, 15 mg/5 mL, 20 mg/15 mL; Tablet: 15 mg

Dosage
?Capsules, Liquid, Lozenges, Syrup, Concentrate, Tablets Antitussive.
Adults and children over 12 years: 10-30 mg q 4-8 hr, not to exceed 120 mg/day; pediatric, 6-12 years: either 5-10 mg q 4 hr or 15 mg q 6-8 hr, not to exceed 60 mg/day; pediatric, 2-6 years: either 2.5-7.5 mg q 4 hr or 7.5 mg q 6-8 hr of the syrup, not to exceed 30 mg/day.
?Sustained-Release Suspension Antitussive.
Adults: 60 mg q 12 hr. Pediatric, 6-12 years: 30 mg q 12 hr, not to exceed 60 mg/day; pediatric, 2-6 years: 15 mg q 12 hr, not to exceed 30 mg/day.